# MTHFR & Methylation Testing - Link: https://myorchidwellness.com/mthfr-methylation-test/ - Published: 2026-10-25T14:27:13-05:00 - Author: Chelsea 👩🏾‍💻 Telehealth available in TX, NY, VA & DC, including **weekends & evening hours** at [telehealth.myorchidwellness.com](https://telehealth.myorchidwellness.com) [Home](https://myorchidwellness.com/)/[Functional Wellness](https://myorchidwellness.com/functional-wellness/)/ MTHFR & Methylation Functional Genetic Testing  •  Carrollton, TX & Telehealth # MTHFR & Methylation Testing:⏎ _Understand Your Genetic Blueprint_ Methylation is a process your body uses constantly to process folate, support detoxification, make neurotransmitters, and repair DNA. An MTHFR and methylation panel looks at common genetic variants in this pathway, so your nutrition and supplement plan can fit how your body works. One-Time Test Cheek Swab or Blood Sample MTHFR C677T & A1298C Methylation Pathway Genes Telehealth Available [Book Your $250 Consultation](https://myorchidwellness.com/mthfr-methylation-test/#book) [What It Measures](https://myorchidwellness.com/mthfr-methylation-test/#measures) About MTHFR & Methylation ## Your genes don’t change.⏎ _Your plan can._ MTHFR is the gene for an enzyme that helps convert folate into its active form, methylfolate. Your body uses methylfolate in methylation, a process involved in processing homocysteine, making neurotransmitters, supporting detoxification, and repairing DNA. Common MTHFR variants, called C677T and A1298C, are found in a large share of the population. Having a variant does not mean you have a health problem; it may mean certain processes work less efficiently. That is why Chelsea interprets your results alongside homocysteine, folate, and B12 levels, plus your symptoms and history. At Orchid Wellness, MTHFR and methylation testing is ordered through your $250 functional consultation with Chelsea Asante, FNP-C. The test is billed separately, and because your genes do not change, it only needs to be done once. [Book Your Consultation](https://myorchidwellness.com/mthfr-methylation-test/#book) MTHFR MTHFR & Methylation Panel Cheek swab or blood sample, depending on the panel MTHFR C677T and A1298C variants Related methylation pathway genes, depending on the panel Interpreted alongside homocysteine, folate, and B12 A one-time test, since your genes do not change Starts With Your Functional Consultation $250 Consultation fee. The MTHFR and methylation panel is billed separately. HSA, FSA, and [Cherry payment plans](https://myorchidwellness.com/cherry/) accepted. What It Measures ## What your methylation⏎ _genes can tell you._ An MTHFR and methylation panel looks at variants like these. Results are always paired with blood work to show how the pathway is actually working. 🧬 ### MTHFR C677T The most studied MTHFR variant, which can reduce how efficiently folate is converted to its active form. May reveal patterns like: One copyTwo copies 🧬 ### MTHFR A1298C A second common MTHFR variant, especially relevant when combined with C677T. May reveal patterns like: Combined variants 🔁 ### Methylation Pathway Genes Depending on the panel, related genes such as MTR, MTRR, COMT, and CBS that affect B12 use, neurotransmitter breakdown, and sulfur metabolism. May reveal patterns like: B12 processingCOMTMethylation support 🩸 ### Homocysteine Context Results are paired with a homocysteine blood level, which shows how well methylation is actually working. May reveal patterns like: HomocysteineFolateB12 💭 ### Mood Pathways Methylation supports the production and breakdown of neurotransmitters linked to mood and focus. May reveal patterns like: Neurotransmitter pathways 🧪 ### Detoxification Support Methylation helps your body process hormones and other compounds. May reveal patterns like: Estrogen metabolismDetox pathways Who It’s For ## If you want a plan built⏎ _around how you’re wired._ 🩸 ### Elevated Homocysteine A high homocysteine level on blood work. 🤰 ### Planning a Pregnancy You are planning a pregnancy and want to talk through your folate and supplement needs. 💊 ### Supplement Reactions You feel unwell on certain B vitamins or methylated supplements and want to understand why. 💭 ### Mood and Focus Concerns Ongoing low mood, anxiety, or focus issues where methylation may be one piece of the picture. 👪 ### Family History A family history of MTHFR variants or elevated homocysteine. 🌱 ### Proactive Optimization You want a personalized supplement plan based on your genetics. The Process ## From consultation⏎ _to answers._ 01 Book Your Consultation Book your $250 functional consultation and complete your intake through your patient portal. Chelsea determines whether the MTHFR panel is right for you. The test is billed separately. 02 Receive Your Kit or Lab Order Depending on the panel, a cheek swab kit is mailed to you or a blood draw is ordered. 03 Collect Your Sample A cheek swab takes just a few minutes at home, or you complete a simple blood draw. 04 Live Results Review Results typically return in about 2 to 4 weeks. Chelsea reviews your genetics with your homocysteine, folate, and B12 levels and builds your plan. Before You Collect ## How to _prepare._ * For a cheek swab, avoid eating, drinking, or brushing your teeth for at least 30 minutes before collecting, or as your kit instructs. * Chelsea may order homocysteine, folate, and B12 blood tests alongside your genetic test. * Follow the kit instructions for collection and shipping. * This test is done once. Your results stay the same for life. Good to Know ## Results, cost, _and safety._ * Results typically return in about 2 to 4 weeks after the lab receives your sample. * Functional testing is direct-pay and not typically covered by insurance. HSA and FSA cards are accepted. * Home kits are mailed to patients in Texas, New York, Virginia, and Washington DC. **Please note:** An MTHFR variant is not a diagnosis. Genetic results describe tendencies, not certainties, and are always interpreted alongside blood work, symptoms, and history. Do not start or change high-dose supplements based on genetic results alone; Chelsea will guide you. Explore All Functional Tests ## Other testing available⏎ _at Orchid Wellness._ The MTHFR and methylation panel is one of several functional tests available through your $250 functional consultation. [Learn about functional wellness](https://myorchidwellness.com/functional-wellness/) HTMA Hair Tissue Mineral Analysis Mineral levels and ratios, plus possible heavy metal exposure patterns, from a small hair sample. Learn more › DUTCH Complete DUTCH Complete Hormone Panel One of the most comprehensive functional hormone tests: sex hormones, cortisol rhythm, melatonin, and metabolites. Learn more › DUTCH Adrenal DUTCH Adrenal Panel Cortisol and DHEA across the day to show how your stress response (HPA axis) is functioning. Learn more › GI-MAP GI-MAP Stool Analysis DNA-based gut assessment covering the microbiome, pathogens, inflammation, and digestion. Learn more › IgG / IgA Food Sensitivity Panel Delayed food reactivity that can guide a structured elimination and reintroduction plan. Learn more › OAT Organic Acids Test Urine-based look at energy production, neurotransmitter metabolites, B vitamins, and yeast markers. Learn more › Micronutrient Intracellular Micronutrient Panel Vitamins, minerals, antioxidants, and amino acids measured at the cellular level. Learn more › MTHFR MTHFR and Methylation Panel Genetic variants in your methylation pathway, interpreted alongside homocysteine, folate, and B12. You are here Frequently Asked Questions ## MTHFR & Methylation _FAQ_ MTHFR stands for methylenetetrahydrofolate reductase, an enzyme that helps convert folate into its active form, methylfolate. Variants in the MTHFR gene can make this enzyme work less efficiently. No. MTHFR variants are very common, and many people who have them never experience problems. Your results are one piece of the picture. Chelsea interprets them alongside homocysteine, folate, B12, and your symptoms before recommending any changes. No. Your genes do not change, so MTHFR and methylation testing only needs to be done once. Follow-up blood work, such as homocysteine, may be repeated to track how your plan is working. Yes. Your intake is completed online, many panels use a home cheek swab, and your results review can be by telehealth in Texas, New York, Virginia, and Washington DC, or in person in Carrollton. Functional testing is generally direct-pay. HSA and FSA cards are accepted, and Cherry payment plans are available to eligible patients. ⌊Chelsea Asante, FNP-C, functional and integrative wellness provider at Orchid Wellness⌉ Ready to Understand Your Genetics ## Your genes tell a story.⏎ _Let’s read it together._ Your $250 functional consultation is your starting point. Chelsea will determine whether the MTHFR and methylation panel is right for you, and the test is billed separately. Results reviews are in person in Carrollton, Texas or by telehealth across Texas, New York, Virginia, and Washington DC. Book your first available appointment at [app.myorchidwellness.com](https://app.myorchidwellness.com), or call or text [(469) 892-0194](https://myorchidwellness.com/mthfr-methylation-test/4698920194). Have your **legal first and last name, email, and phone number** ready. 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Payment plans are offered through Cherry and are subject to approval. Rates range from 0% to 35.99% APR based on eligibility. Cherry is not the lender.